Showing posts with label DT Presents. Show all posts
Showing posts with label DT Presents. Show all posts

Saturday, December 12, 2009

DT presents: Important Proteins in Cancer that are also Related to Music!!!

MGMT:

  • Popular indie band alleged to have given Bernice a cookie once, short for management
  • Important DNA repair protein and tumor suppressor, short for O-6-methylguanine-DNA methyltransferase

Ras:

  • Reggae record label
  • Potent oncogene implicated in a large proportion of human cancers. Kinase located upstream in many signalling pathways

Myc:

  • The Music for Young Children program
  • Potent oncogene that stimulates proliferation and DNA damage among other things

P27:

  • Seminal Swiss rap group, known to perform with a full funk band backing them
  • Inhibitor of CDKs important to cell cycle progression. Subcellular localization has been tied to prognosis.

MMP:

  • Polish record label. Short for Metal Mind Productions (robots!!!!!)
  • Short for matrix metalloproteinase. Important protein in metastasis, cleaves basement membrane fibers releasing growth factors and clearing space. Secreted from tumor associated macrophages and transformed epithelial cells.

Slug:

  • Rapper from Minneapolis
  • C2H2 transcription factor. Down regulates E-cadherin. Implicated in cancer, probably through EMT.

Functional Death Receptor:

  • Metal band from Green Bay. Claim to mix heavy metal with death metal as well as doom metal. Check out their Myspace!!!
  • working cell receptor that binds ligands triggering apoptosis. Loss of function can lead to cancer.

P53:

  • Imporvisational music group with weirdly extensive wikipedia page
  • The gaurdian of the whole fuckin' genome! Probably the most important tumor supressor in the biz. Controls a wide variety of processes inculding apoptosis and progression through the cell cycle

Coincidence? I think not.

In other news the guy beside me in the library has been stroking his chubby girlfriend's enormous ass for the entire amount of time it took me to right this. What is up with that?